Pacylex Pharmaceuticals Announces Publication in Nature Communications of a New Target for Therapeutic Intervention in Hematologic Malignancies and Preclinical Results of a First-in-Class Therapy

Edmonton, Alberta--(Newsfile Corp. - October 22, 2020) - To view the full announcement, including downloadable images, bios, and more, click here.

Key Takeaways:

• Data published in Nature Communications shows NMT inhibitor effective against many cancer cell lines, especially blood cancers including lymphoma and leukemia
• Pacylex was founded on the insight that there is a connection between myristoylation and cancer, which presented a target that had never been fully explored for potential human therapy.
• Establishes proof-of-concept for NMT inhibitors as potential cancer therapeutics and supports the continued preparation for the first human clinical trial set to begin in early 2021.

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About Pacylex
Pacylex is a pre-clinical pharmaceutical company targeting hematologic cancers with a new first-in-class therapeutic, and is headquartered in Edmonton, Alberta, Canada. Pacylex's technology combines new insights from Dr. Luc Berthiaume of the University of Alberta, connecting myristoylation to cancer, with a family of high quality myristoylation inhibitors Pacylex licensed the molecules from the University of Dundee in 2015. PCLX-001 is the lead drug in a new class of NMT inhibitors, enabling us to exploit NMTs as new clinical targets for cancer treatment. Pacylex completed GLP toxicology on PCLX-001 and expects to file soon for regulatory authorization to commence clinical studies in Canada in early 2021 in diffuse large B-cell lymphoma and solid tumors.

Contacts:

Michael Weickert Ph.D
650-218-1840
michael.weickert@pacylex.com

Source: Pacylex

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/66629