Hemostemix Announces Grant of Stock Options

Calgary, Alberta--(Newsfile Corp. - January 4, 2021) - Hemostemix Inc. (TSXV: HEM) (OTC: HMTXF) ("Hemostemix" or the "Company") announces that, in accordance with its stock option plan, it has granted on December 31, 2020, subject to regulatory approval, a total of 5,274,500 stock options to purchase common shares of ‎Hemostemix (the "Options") to directors, officers, employees and consultants of Hemostemix. Of the Options granted 3,887,100 vest immediately and 1,387,400 vest 50% immediately and 50% on December, 31 2021. All options were granted with an exercise price of $0.70 per common share and have an expiry date of December 31, 2025. After ‎this Option issuance, Hemostemix has 5,342,000 Options issued and outstanding.

‎Of the 5,274,500 Options granted, 2,914,400 Options were issued to directors and officers of Hemostemix. Hemostemix relied on section 5.5(b) of Multilateral Instrument 61-101 - Protection of Minority ‎Security Holders in ‎Special Transactions ‎‎("MI 61-‎‎101")‎ as the exemption from the formal ‎‎valuation ‎requirements of MI 61-101 and TSX Venture Exchange Policy 5.9 in respect of the ‎Options grant to the directors and ‎officers of Hemostemix as no securities of ‎Hemostemix are listed on a ‎specified market as defined in MI 61-101. Hemostemix relied on section ‎‎5.7(a) of MI 61-101 as the exemption from ‎the minority approval ‎requirements of MI 61-101 and TSX Venture Exchange Policy 5.9 ‎in ‎respect ‎of the Options grant to the directors and officers of Hemostemix as neither the fair ‎‎market value of the subject matter of, nor the fair market value ‎of the consideration for, the Options granted to the directors and officers of the Company exceeded 25% of Hemostemix's ‎‎market capitalization.‎‎ The Compensation Committee and Board of Directors of the Company have approved the Options grant and no materially contrary view or ‎abstention ‎was expressed or made by any director in relation to the Options grant.‎ The material change report to be filed in relation to the Options grant will not be not filed at ‎least 21 days prior to the completion of the Options grant as ‎contemplated by MI ‎‎61-101. The Company believes that this shorter period is reasonable and ‎necessary in the ‎circumstances as the completion of the Options grant occurred shortly before the ‎issuance of this news release and the filing of such material change report.‎

ABOUT HEMOSTEMIX

Hemostemix is a publicly traded autologous stem cell therapy company, founded in 2003. A winner of the World Economic Forum Technology Pioneer Award, the Company developed and is commercializing its lead product ACP-01 for the treatment of CLI, PAD, Angina, Ischemic Cardiomyopathy, Dilated Cardiomyopathy and other conditions of ischemia. ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation.

On October 21, 2019, the Company announced the results from its Phase II CLI trial abstract presentation entitled "Autologous Stem Cell Treatment for CLI Patients with No Revascularization Options: An Update of the Hemostemix ACP-01 Trial With 4.5 Year Follow-up" which noted healing of ulcers and resolution of ischemic rest pain occurred in 83% of patients, with outcomes maintained for up to 4.5 years.

The Company owns 91 patents across five patent families titled: Regulating Stem Cells, In Vitro Techniques for use with Stem Cells, Production from Blood of Cells of Neural Lineage, and Automated Cell Therapy. For more information, please visit www.hemostemix.com.

For further information, please contact:

Thomas Smeenk, President, CEO & Co-Founder
Suite 1150, 707 - 7th Avenue S.W., Calgary, Alberta T2P 3H6
Phone: 905-580-4170

Neither the TSX Venture Exchange nor its Regulation Service Provider (as that term is defined under the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release.

Forward-Looking Information: This news release contains "forward-looking information" within the meaning of applicable Canadian securities legislation. All statements, other than statements of historical fact, included herein are forward-looking information. In particular, ‎this news release contains forward-looking information in relation to: the commercialization of ACP-01. ‎‎There can be no assurance that such forward-looking information will ‎prove to be accurate. Actual results and future events could differ materially from those anticipated in such forward-looking ‎information. This forward-looking information reflects Hemostemix's current beliefs and is based on information currently ‎available to Hemostemix and on assumptions Hemostemix believes are reasonable. These assumptions include, but are not ‎limited to: the underlying value of Hemostemix and its common shares; the successful resolution of the litigation that Hemostemix is pursuing or defending (the ‎‎"Litigation"); the results of ACP-01 research, trials studies and analysis, including the midpoint analysis, being equivalent ‎to or better than previous research, trials or studies as well as management's ‎expectations of anticipated results; ‎Hemostemix's general and administrative costs remaining constant; the receipt of all required regulatory ‎approvals for ‎research, trials or studies; the level of activity, market acceptance and market trends in the healthcare sector; the ‎economy ‎generally; consumer ‎interest in Hemostemix's services and products; competition and ‎Hemostemix's competitive advantages; ‎and Hemostemix obtaining satisfactory financing to ‎fund Hemostemix's operations including any research, trials or studies, ‎and the Litigation. Forward-looking information is subject to known and unknown risks, uncertainties and other factors that ‎may cause the actual results, level of activity, performance or achievements of Hemostemix to be materially different from ‎those expressed or implied by such forward-looking information. Such risks and other factors may include, but are not ‎limited to: the ability of Hemostemix to complete its current CLI clinical trial, complete a satisfactory futility analysis and the ‎results of such and future clinical ‎trials; ‎litigation and potential litigation that Hemostemix may face; general business, ‎economic, competitive, political and social uncertainties; general capital market conditions and market prices for securities; ‎delay or failure to receive board or regulatory approvals; the actual results of future operations including the actual results ‎of future research, trials or studies; competition; changes in legislation ‎affecting Hemostemix; the timing and availability of ‎external financing on acceptable terms; long-term capital requirements and future developments in Hemostemix's markets ‎and the markets in which it expects to compete;‎ lack of qualified, skilled labour or loss of key individuals; and risks ‎related ‎to the COVID-19 pandemic including various recommendations, orders and measures of governmental authorities to ‎try to ‎limit the pandemic, including travel restrictions, border closures, non-essential business closures, ‎service disruptions, ‎quarantines, self-isolations, shelters-in-place and social distancing, disruptions to markets, disruptions to economic activity ‎and ‎financings, disruptions to supply chains and sales channels, and a deterioration of general economic conditions ‎including a ‎possible national or global recession or depression; the potential impact that the COVID-19 pandemic may have ‎on Hemostemix may include a decreased demand for the services that Hemostemix ‎offers; and a deterioration of financial ‎markets that could limit Hemostemix's ability to obtain external financing. A description of additional risk factors that may ‎cause actual results to differ materially from forward-looking information can be found in Hemostemix's disclosure ‎documents on the SEDAR website at www.sedar.com. Although Hemostemix has attempted to identify important factors that ‎could cause actual results to differ materially from those contained in forward-looking information, there may be other ‎factors that cause results not to be as anticipated, estimated or intended. Readers are cautioned that the foregoing list of ‎factors is not exhaustive. Readers are further cautioned not to place undue reliance on forward-looking information as there ‎can be no assurance that the plans, intentions or expectations upon which they are placed will occur. Forward-looking ‎information contained in this news release is expressly qualified by this cautionary statement. The forward-looking ‎information contained in this news release represents the expectations of Hemostemix as of the date of this news release and, ‎accordingly, it is subject to change after such date. However, Hemostemix expressly disclaims any intention or obligation to ‎update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except ‎as expressly required by applicable securities law.‎

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