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Athletes’ desire to achieve peak performance requires significant physical exertion with little time for recovery. The physical demands without sufficient time for recovery lead to increased risk for injury and overall fatigue. Dietary supplements and other ergogenic aids have become staples for athletic populations to push boundaries and recover faster. Recovery products typically include amino acids, antioxidants, and botanically-derived supplements. Cannabidiol (CBD), derived from hemp, has grown in popularity due to its potential benefits including anti-inflammatory, pain and sleep support. The World Anti-Doping Agency (WADA) removed isolated CBD from the prohibited list, further expanding acceptance of products containing CBD for athletes’ recovery programs. A recent systematic review explored studies on CBD for sports recovery using established criterion for determining which studies should be included in the review. Over 2/3 of the data came from preclinical and clinical studies in a multitude of subjects spanning from rodents or porcine animal models to human studies. Overall, results from both animal and human studies reviewed indicate CBD has significant potential for recovery through its anti-inflammatory properties. Results from our human clinical study corroborate the potential benefits for CBD as a component of a recovery program. Healthy human subjects who consumed CBD over 90 days experienced significantly less pain compared to the placebo group via surveys and analysis of biomarkers for pain. We will continue to share more data on the benefits of cannabinoids and other functional ingredients as it becomes available. #CBDBenefits #CBDWellness #SportsRecovery #Research #Cannabinoids https://lnkd.in/evYtYhSt

The number of Americans who are struggling with obesity continues to increase every year. The CDC released new data from 2022 showing 22 states have an adult obesity prevalence at or above 35%, representing an increase over just 10 years ago. Obesity predisposes impacted individuals to a multitude of additional adverse medical conditions. Americans are increasingly focused on how to improve their health and wellness and therefore, are looking to non-pharmaceutical options which include hemp-derived cannabinoid products. The growing body of scientific literature supporting the benefits of hemp-derived cannabinoids includes studies exploring the benefits of tetrahydrocannabivarin (THCV). THCV is a naturally occurring phytocannabinoid present in small quantities in Cannabis sativa L. The data indicates it does not contribute to psychoactive effects, rather it appears to support a healthy metabolic profile with positive effects on energy expenditure, body weight, and blood glucose. A recent study explored the benefits of combinations of low levels of cannabidiol (CBD) + THCV in obese adults who were otherwise healthy. Subjects were given one of two doses of the test product (Group A: 10 mg CBD + 8 mg THCV; or Group B: 20 mg CBD + 10 mg THCV) once daily for 90 days. Subjects in both groups experienced significant weight loss and reductions to abdominal girth over time and compared to the placebo group.  Systolic blood pressure improved over time for Group A and total cholesterol numbers improved over time for Group B. LDL values improved for both groups over the study duration. This study supports the benefits of consuming THCV + CBD on metabolic indices over time. cbdMD recently released our THCV+CBG Energy softgels in recognition of the potential benefits from consuming a product containing THCV. We continue to prioritize our customers’ well-being and provide innovative, quality products, like our Energy softgels for their unique needs. We will share more data on THCV as it becomes available. https://lnkd.in/eKQQrSsx #cannabinoids #THCV #botanicals #research #innovation

cbdMD Launches Max Chill Dragon Fruit D9 Gummies Crafted to elevate summer unwind sessions, these gummies boast a distinctive 1:1 CBD to THC ratio, marking a milestone in the brand's selection of high-mg THC products. Each gummy contains 10 mg of Delta 9 THC and 10 mg of CBD, ensuring a balanced experience. This equal ratio harnesses the synergy between THC and CBD to maximize relaxation benefits. CBD's ability to promote relaxation and counteract potential negative sensations associated with THC makes the combination ideal for unwinding and relieving daily stress. "At cbdMD, we're committed to continually enhancing our customers' journeys, and this new product epitomizes that commitment," expressed Ronan Kennedy, CEO at cbdMD. "We formulated this product with a specific goal in mind: to offer a Farm Bill compliant high mg THC product designed to help reduce daily stress and promote relaxation. Our dedication to providing a premium experience extends to prioritizing our customers' well-being, and we're proud to offer a product that not only delivers on potency but also promotes a positive and enjoyable experience just in time for Summer." https://lnkd.in/e78CXxiz

Many Americans struggle daily with pain. Depending on the level and severity of pain, the options for alleviating it often come with significant side effects of their own. Therefore, consumers seek natural options to avoid those side effects while addressing their discomfort. Botanically derived solutions for discomfort are growing in popularity, including hemp-derived products containing cannabidiol (CBD) and tetrahydrocannabinol (THC). An observational, prospective study was completed in Israel by physicians who routinely rely on medical cannabis for management of chronic pain. Participants were provided with set combinations of THC and CBD extracts ranging from 20% THC + 4% CBD to no THC + 24% CBD. The ratios were selected by the physicians in recognition that different ratios of THC:CBD would benefit the participants in distinct ways. The data reflected a significant improvement in pain compared to baseline at all of the timepoints measured. The largest decrease in reported pain (-14%) occurred after six months of treatment. The study participants also reported a decrease in other symptoms of extended pain, including a decrease in instances and severity of sleep disruption and mood, which led to an overall positive impact on their quality of life. This study adds to a growing body of literature supporting the benefits of hemp-derived products for discomfort and pain. cbdMD appreciates the fact that different ratios are appropriate for different people. We offer a variety of formulations carefully curated for our customers with diverse combinations of cannabinoids to address their unique, individual needs. Stay tuned for more information on new product launches, which will expand our portfolio of hemp-derived products. #CBDresearch #CBDWellness #CBDBenefits #Cannabinoids https://lnkd.in/ernhnEti

Ganoderma spp., or Reishi, is a genus of macrofungi known for its beneficial properties, which includes but is not limited to neuroprotection, antioxidant, and anti-inflammatory benefits. One of the most prevalent species in dietary supplements is Ganoderma lucidum (G. lucidum) with extensively studied bioactive compounds found in its fruiting body, mycelia, and spores. When considering the benefits of functional mushrooms, it’s also important to understand their composition. A recent study published in Foods explored the nutrient and phytochemical composition of species of Ganoderma, including Ganoderma lucidum. G. lucidum contains dietary fiber and minerals, including calcium, magnesium, iron, and zinc, all contributing to the antioxidant and immune supporting benefits supported by scientific literature. G. lucidum also contains an abundant quantity of amino acids, including essential amino acids (histidine, leucine, lysine, methionine, phenylalanine, threonine, and valine). This species of Ganoderma also contains unsaturated fatty acids (linoleic and oleic acid), which are associated with heart health. The antioxidant benefits often associated with supplementation of G. lucidum are attributable to its triterpenoid, flavonoid, and primary polyphenol content. These bioactive compounds demonstrated antioxidant effects in the study in Foods via free radical scavenging (DPPH+ and ABTS+). cbdMD’s sister brand, ATRx Labs, formulated its Ultimate Mushroom Daily Gummy with a blend of functional mushrooms including Cordyceps, Lion’s Mane, and Reishi in combination with nootropics, Huperzine A and L-theanine to bring our customers a functional wellness product with benefits including those described in the article today. We anticipate future additions to the functional mushroom line in ATRx Labs in recognition of the growing body of literature supporting their benefits. We will continue to share data on the benefits of functional mushrooms and other botanical ingredients as it becomes available. https://lnkd.in/ePM6EP2j #functionalnutrition #functionalmushrooms #innovation #researchanddevelopment

Hericium erinaceus (Lion’s Mane) is an edible mushroom known for its numerous health promoting benefits, including potential neuroprotective and neuroregenerative properties. H. erinaceus contains several bioactive components including polysaccharides, phenolic acids, and terpenoids, such as hericenones and erinacines. Both hericenones and erinacines cross the blood-brain barrier, exerting neuroprotective and cognition-enhancing effects. Human studies indicate supplementation with H. erinaceus improve cognition in older adults with cognitive impairment. Supplementation with H. erinaceus has also been associated with reductions in depression, anxiety and sleep disorder scores.   A study published in Nutrients explored the short and long term effects of supplementation with H. erinaceus in healthy adults using a randomized, placebo-controlled, double-blinded, parallel-group study design. Participants consumed placebo or 3 capsules daily (600 mg H. erinaceus per capsule) for 28 days. Cognitive processing speed was increased in participants who consumed one dose of H. erinaceus. Consumption for 28 days was associated with a trend toward lower self-reported scores for stress. This study adds to the growing body of literature supporting the cognitive and mood benefits associated with consumption of functional mushrooms.   In recognition of the benefits of functional mushrooms, cbdMD launched its functional mushroom line through its sister brand, ATRx Labs. We anticipate future additions to the line to offer our customers efficacious products for specific areas that matter to them.   We will continue to share data on the benefits of functional mushrooms and other botanical ingredients as it becomes available.   https://lnkd.in/egPV62F6   #functionalnutrition #functionalmushrooms #innovation #researchanddevelopment

In continued recognition of the month of April being National Stress Awareness Month, we are sharing another study exploring nonpharmaceutical options for stress. Many of those impacted by anxiety find the treatment often comes with side effects that prove to be deterrents to continued use of the medications, including cognitive or sexual dysfunction. Consumers are therefore seeking options that are naturally derived, nonpharmaceutical to avoid the side effects. Botanical-derived solutions are increasing in popularity for their perceived benefits without the detractors commonly associated with pharmaceutical treatment.   Investigators in Boston completed an open label stage of a human clinical trial which investigated the benefits of full spectrum hemp extract on measures of anxiety in adults. The study enrolled fourteen adults with moderate to severe anxiety who were currently being treated for this disorder. Participants consumed full spectrum hemp extract tinctures containing 10 mg CBD and 0.23 mg THC three times daily for four weeks. At the completion of the study participants demonstrated significant reductions in all indices of anxiety relative to their baseline data, with a significant response to treatment occurring as early as one week into the study which was maintained throughout the study (>15% reduction). Study participants did not experience negative side effects related to the test product.   We previously completed a human clinical study that provided 100 mg CBD daily for 90 days to healthy male and female subjects. Female participants who received the test product reported significantly less stress compared to the placebo group. Furthermore, the dose of cannabinoids provided to participants in the study discussed today and our human clinical were significantly lower than previous doses administered in clinical studies which demonstrated efficacy. This data further supports the benefit of cannabinoids for mental health and wellness. We will continue to share more data on the benefits of CBD and other cannabinoids as it is published.   #CBDWellness #CBDBenefits #Research #Cannabinoids https://lnkd.in/dHDkzaTT

April is recognized as National Stress Awareness Month in recognition of the negative impact stress may have on overall health and wellness. The impact of stress on overall health may not always be apparent. It contributes to sleep disruption, headache, increased propensity of illness and changes to your mood. When left untreated stress can lead to health issues, including high blood pressure, heart disease, stroke, obesity, diabetes, and mental illness.    Humans are not the only ones who experience stressors that take a toll on overall health. Dogs often experience stress from being alone, kenneling, or traveling in cars. Pet owners have sought treatment options including pharmaceutical interventions, behavioral therapies, or nutraceuticals with varying degrees of success.   A recent study published in the Journal of Animal Science explored the benefits of cannabidiol (CBD) for dogs with travel-related anxiety. Dogs were given CBD in capsule form (4 mg/kg) daily for 24 weeks and then tested two hours after administration at weeks 0. 8, 16, and 24. Serum assays and behavioral assessments were performed at each time point to determine if the treatment was efficacious. Traveling in the car elicited a stress response in several measures for both groups including changes in cortisol, heart rate (HR), HR variability, lip licking and yawning. Although the stress response was less prominent by week 24, dogs that received CBD daily exhibited a significantly lesser response to the stressor in some of the measures of stress.   The data from this study corroborates similar studies in human populations. We completed a human clinical in healthy populations which administered 100 mg/CBD daily and explored indices of stress and tension/anxiety over time. Our study determined that 100 mg of CBD resulted in an 11% reduction in stress scores for female subjects and a trend for 19% lower tension/anxiety scores for both male and female subjects over the 90-day study. Although additional studies are always welcome, there is a growing body of literature supporting the positive impact of low dose CBD consumption in dogs and humans.   We will continue to share more data on the benefits of CBD and other cannabinoids as it is published.   #CBDWellness #CBDbenefits #Research #Cannabinoids   https://lnkd.in/euWk7gDm

Modern medicine and lifestyle changes have led to an increasingly longer lifespan for American adults. The population of elderly individuals has also increased, along with demand for functional products to support healthy aging. While it is generally expected that physical ailments increase with age, more evidence has emerged regarding the increasing prevalence of mental aspects of aging, particularly cognitive and memory decline.   Consumers are seeking natural options to support their health and wellness, which has recently been demonstrated by increased interest in functional mushrooms. Lion’s Mane (Hericium erinaceus) mushroom is known for its role in promoting overall health, which is attributed to the over seventy bioactive metabolites it produces, including ß-glucans, eracines, and hericenones. Lion’s Mane has also been studied for its antioxidant, anti-senescence, and neuroprotective properties. A recent study in Biology investigated the effects of oral supplementation with Lion’s Mane extract for two months in an aging mouse model. After two months of supplementation with lion’s mane extract, the mice exhibited an altered composition of intestinal bacteria, which resulted in an increase in key genera related to cognition and concurrent decrease in genera associated with inflammation. Further, supplementation with Lion’s Mane positively modulated markers for neurodegeneration by supporting architecture of specific regions of the brain and decreased markers for neuroinflammation in the hippocampus. This study provides support for the benefits associated with consumption of lion’s mane mushroom extract for cognition and also indicates Lion’s Mane may also support gut health. There is a growing body of literature suggesting a connection between gut health and the central nervous system. Studies indicate the type of microbiota in the gut impact memory and cognition. Data indicates that when microbial diversity decreases and incidence of proinflammatory species increases there is a commensurate increase in pervasiveness of cognitive impairment. This study adds additional support to the correlation between gut health and cognitive function.   We launched a line of functional mushroom products last year through our sister brand, ATRx Labs. The Super Mushroom gummy is the first product to be released with a blend of functional mushrooms, including Cordyceps, Lion’s Mane, and Reishi mushrooms with Huperzine A and L-Theanine to support cognition and mood. In recognition of the growing body of literature supporting the benefits of functional mushrooms, we anticipate future additions to the functional mushroom line in ATRx Labs.   We will continue to share data on the benefits of functional mushrooms and other botanical ingredients as it becomes available. #functionalnutrition #functionalmushrooms #innovation #researchanddevelopment https://lnkd.in/e6KKKiHq

An increasing number of Americans suffer from mental health challenges, which is occurring in conjunction with a significant drop in sleep quality and hours of sleep per night. Almost a third of adults in America get less than hours per night of sleep. Research on this subject helped to support an increase in the prevalence of natural alternatives for sleep support.   A recent study of out the University of Northern Colorado investigated the effects of eight weeks of oral consumption of 50 mg of cannabidiol (CBD) in a liquid gelcap on indices of sleep quality. Subject who consumed 50 mg of CBD for eight weeks reported significant improvement in scores on Leeds sleep evaluation questionnaire. Further, when study participants were asked to rate their quality of sleep when they woke after consuming CBD, they reported over 79% improvement compared to a 24.5% improvement in the control group. This data provides further support that regular use of CBD may help to improve the quality of sleep in healthy subjects.   cbdMD is partnering with Whoop to explore the benefits of 100 mg our broad spectrum hemp extract on sleep and recovery in healthy subjects over 90 days. Participants are wearing bands to collect objective biometric data on parameters for recovery and sleep. Study participants are also completing journals to provide insight into their perspective on sleep and recovery metrics during the study. We expect to report the results from the study later this year.   We will continue to share data on the benefits of cannabinoids and other functional ingredients as it becomes available.   #CBDwellness #CBDBenefits #Research #Cannabinoids   https://lnkd.in/ertU4mY6